About the Project
Organoids will be studied to better understand the aberrant pathways underlying colorectal cancer and pancreatic cancer, especially with focus on EGFR signaling and anti-EGFR-therapy and mutations in the Ras driver and experimental Ras inhibitors. Blood and normal liver and pancreas will be banked for studies combining epithelial cell organoids with immune cells. Organoids will remain at UCSF.